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What is FFR?

Published By : Boston Scientific

Published On : Jan 9, 2019 10:07:32 AM

Interventional Cardiology

WHAT IS FFR?

FFR is the maximum flow down a vessel in the presence of stenosis compared to maximum flow in the hypothetical absence of the stenosis.

Pd = distal pressure

Pa = aortic pressure

Pd/Pa + hyperemia = FFR

 

CLINICALLY SPEAKING

FAME I RESULTS | Fractional Flow Reserve Versus Angiography for Multivessel Evaluation (F.A.M.E.)

  •   The FFR group performed significantly better in MACE-free survival 30–360 days

  •   The FFR group was statistically significant in Death/MI and MACE but improved in all metrics vs. the angio-guided group

 

WHAT THE NUMBERS SAY

FAME II RESULTS | Demonstrated that PCI was superior to medical therapy with FFR > 0.81>

  •   FAME II randomized patients with FFR < 0.8 to PCI + MT or MT compared to patients with FFR > 0.8 who received MT

  •   83% Relative risk reduction in urgent revascularization in FFR PCI + MT group

† Relative risk reduction

 

FFR VS. ANGIO-GUIDED PROCEDURES

More quality outcomes. Reduced costs.

  •   Over a 1-year period, FFR reduced MACE, MI, and death up to 40%

  •   Savings of $2,385 per patient over one year in patients with multi vessel disease*

  •   FFR reduced costly adverse events

  •   FFE provides accurate diagnosis to reduce costs

* Hospital savings are based on calculations by Boston Scientific

 

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